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Manna Pro Opti-Zyme

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Manna Pro Opti-Zyme


In Stock. Usually Ships within 24 hours.

Shipping weight = 3.25 lbs.


Product Summary:

Manna Pro® Opti-Zyme®

Manna Pro® Opti-Zyme® probiotic supplement is made with naturally viable yeast, enzymes and beneficial bacteria to promote optimal digestion. This easy-to-feed meal formula is highly palatable and can be top dressed with your horse's feed.


  • Natural probiotic ingredients help promote optimal digestion
  • Easy to feed
  • Use in horses, cattle, pigs, sheep, and goats
Item Specifications:

Daily Dosage:
2 oz. per 1,000 lb. of body weight

3 lb. (up to 24 days supply)

Guaranteed Anaylsis:
Saccharomyces: 158 x 109 CFU/lb
Enterococcus Faecium: 0.79 x 109 CFU/lb
Lactobacillus Casei: 0.31 x 109 CFU/lb
Lactobacillus Plantarum: 158 x 109 CFU/lb
Amylase*: 17,875 BAU/lb
Protease*: 18,750 CDU/lb
Hemicellulase*: 1,585 HCU/lb
Betaglucanase*: 11,440 BGU/lb
*Source of Naturally Occuring Viable Yeast, Enzymes and Bacteria For Use in Animal Feeds

Yeast culture, saccharomyces cervisiae, dried enterococcus faecium fermentation product, dried lactobacillus casei, dried lactobacillus acidophilus fermentation product, dried lactobacillus plantarum, dried bacillus subtilis fermentation product, dried aspergillus oryzae fermentation extract.

Feeding Directions
Top dress at the following levels:
Horse: 1-2 oz./head/day
Beef & Dairy Cattle: 1-2 oz./head/day
Swine: 0.25-0.50 oz./head/day
Sheep: 0.25-0.50 oz./head/day
Goats: 0.25-0.50 oz./head/day

For those who mix their own feed:
Opti-Zyme® can be added to the grain mix at the rate of 10 to 15 lb/T.

PLEASE NOTE: Date on package is manufacture date, not an expiration.

For Product Label Information, please click on Manufacturer Information to the right.

Downloadable Resources
Product LabelManufacturer Information
Item Number Model Number UPC
SLT901026 1000082 095668994921
Additional Information:
Legal Disclaimer - This product contains chemicals known to the State of California to cause cancer and birth defects or other reproductive harm. For more information, go to

Product Reviews by Customers

4.9 / 5.0
25 Reviews
5 Stars
4 Stars
3 Stars
2 Stars
1 Star
4.7 / 5
4.6 / 5
Recommend to a Friend
Yes (19)
Really liking it
After reading other reviews i put one of my horses on this he gets diahrea during winter and in one week it has improved his health no more diahrea and almost into 3weeks of feeding it now. And I have recommended it to a niebour.
November 3, 2017
12 months ago
Opti-Zyme keeps my horses healthy.
I have been using Opti-Zyme once a day for both of my horses. I have used this product for 5 years consistently and I truly believe it works to keep their digestive tract in great working order!
September 22, 2017
1 year ago
For horses that need prebiotics
We spent the winter in Arizona and found out my horse was allergic to mixed alfalfa and Bermuda grass. Found oupt about opti zyme and gave it to him each morning with his mash. Within a day his runs stopped andhe had a lot more energy and comfort.
June 13, 2017
Mana Pro Opti-Zyme is good stuff
My horse was low Amylase... tough to digest grain in hind gut if Amylase is low. she is looking much better after 4 weeks... cant wait for the 2 month point. Vet recommended and horse likes it when mixed well in morning grain. My 16 2 Quarter mare was 200lbs down when I got her. Terrible feet and digestion problems. Mana Pro Sho Hoof and this product have really helped. Blood Profile and CBC already showing major improvement. Low Amylase is common in horses that are or have a lot of thoroughbred in back breeding.
July 28, 2016
Trial period 2nd purchase
Went thru one bag for 2 mares. One mare has more issues with loose stools. This product seems to have helped so I will keep using it. It may take another month to really make a difference.
June 30, 2016
I take probiotics, my animals do, too. and this one works great for my horses.
May 27, 2016
This seems to agree with my mares
This probotics seems to be agreeing with my mares and helps me know that they are getting what they need.
May 16, 2016
Cured My Horse of chronic loose stools.
My horse is 18 yrs of age. I have had him for 15 yrs and he has always had chronic loose stools. Manna Pro Opti -Zyme has cured his loose stools. His stools are normal now giving him a full scoop AM and PM daily.
August 8, 2015
Works and easy to give
My mare had loose stools and needed the extra probiotics/enzymes. She eats this right up by itself, in fact, I used this to hide her medication in and she had no problem eating it all up so I didn't have to force feed it to her. Her stools cleared up within 2 days and now I give this as a supplement on top of grain to both my horses, it keeps them both fat and happy.
July 10, 2015
Best overall product for digestive and loose manure I've come across at a great price. It really works well!!!
June 9, 2015
Start typing your question and we'll check if it was already asked and answered. Learn More
Browse 7 questions Browse 7 questions and 79 answers
Why did you choose this? Store
My horse has a history of gas colic, and we haven't had a problem since starting him on the Opti-Zyme (knock on wood!) He had been on a different probiotic previously, without this degree of success.
CINDY H on Aug 19, 2018
Helped my horse with laminitis.
JOAN A on Jul 18, 2017
My horse has a history of gas colic, and we haven't had a problem since starting him on the Opti-Zyme (knock on wood!) He had been on a different probiotic previously, without this degree of success.
CINDY H on Aug 19, 2018
Great for hard keepers, helps keep weight on without over feeding.
JOY M on Apr 17, 2018
Helped my horse with laminitis.
JOAN A on Jul 18, 2017
I ride endurance, and this product helps with eating while under stress, which in turn helps to curb ulcers. I have noticed a change in my horse at competitions.
SABRINA L on Jun 16, 2017
My horses have been on this for a year and a half and are doing great. This vendor is significantly less expensive than anywhere else to purchase, and much more convenient than having to stop in a store.
Stacey B on May 15, 2017
Works great, cost effective
CAROLYN S on Apr 20, 2017
i have 3 horses over 24 and vet recomended for that age of horse..
sharon k on Feb 28, 2017
A friend recommended this supplement to me for my aged mare. I have been feeding it for the past two years and I feel that it has helped her maintain her weight.
JOYCE F on Dec 30, 2016
Good product.
Frank S on Sep 23, 2016
Sounds like what my mare needs to get rid of loose stools and get her system going right.
Valerie S on May 21, 2016
recommended by vet
Maggie P on Mar 9, 2016
I used it for my rescue horse, who doesn't seem to poop as much as he should and doesn't always eat all his hay. Since I've started, he eats more and poops more!
Katelynn M on Dec 13, 2015
All five horses will eat this and it clearly has helped at least one of them gain significant (actually too much!) weight. Also the manure is noticeably smaller/more compact.
L O on Sep 15, 2015
The equine nutritionist at our local Southern States recommended this supplement for my nervous and my ulcery horses. Less expensive than several other brands and my horses seem content.
ILKA M on Jun 23, 2015
Great stuff. Stopped watery stools for my horse.
ANGIE S on Jun 14, 2015
My horse will eat this supplement in her feed when she will not eat any others and she is not a picky eater.
Inger E on Apr 22, 2015
I have been using this for awhile now for my older horses and have now started using it for my young. And the price is great.
LOIS K on Mar 30, 2015
Needed and good pricing!
TERY S on Oct 20, 2014
I use Opti-Zyme because it is crucial to keep a horses intestines moving. I don't get to ride as much as I would like to. My mare goes at least four times from the afternoon feeding till the morning.This a great product!
STEVE G on Oct 17, 2014
Price is good
jill a on Sep 21, 2014
Recommended by other horse professionals, including my horse's sports therapist
Elizabeth L on Apr 23, 2014
my mare of 17 yrs. has digestive issue and this product has helped stabilize her.
PAT S on Apr 7, 2014
because my horses have done very well on it for several years.
LYNN R on Apr 5, 2014
Really slicks up a horse and promotes great feed conversion.
L A on Mar 17, 2014
helps my old mare digest her food better
bina a. g on Mar 16, 2014
I have been feeding this to my horses for the last 6 months. The winter was very cold and I wanted to help my horses keep and maintain their weight in the extreme cold weather.
RUTH M on Mar 11, 2014
Great for hard keepers, helps keep weight on without over feeding.
JOY M on Apr 17, 2018
I ride endurance, and this product helps with eating while under stress, which in turn helps to curb ulcers. I have noticed a change in my horse at competitions.
SABRINA L on Jun 16, 2017
is this pelleted, or powder?
A shopper on Nov 10, 2014
BEST ANSWER: It is a course powder. It mixes well into a grain feed but I put a little water into a pelletted feed so the Opti-Zyme sticks better, otherwise it willl sift to the bottom of the grain bucket.
I just started my older gelding on this supplement, he is underweight with loose stools. His stool is watery now, is this normal? I didn't know if I should give it a little more time, or if he should have shown improvement right away. Did anyone else's horses stool get worse when they first started in this?
Andrea M on Nov 10, 2016
BEST ANSWER: My mare did because it's adding enzymes to help move things along and help break down and digest, my vet said it was fine but should last more then a couple weeks. But really depends on your horses health and what diet you have them on. My mare was fine within a week and after a month use I noticed she wasn't so gut sensitive, consult a vet if your concerned. Used it for months and saw improvement
My 28 year old horse after using opti zyme a couple of days was acting like he was going to colic. After two days off his feed, tonight I only gave him his senior feed without the opti zyme and he ate it. Are there any cases where this product is not appealing to a horse or could it have made him colic mildly?.
A shopper on Mar 8, 2016
BEST ANSWER: I don't know about it giving horses colic. I use it to help my horses digest their food better. I even give extra to my 26 year old who has digestive issues. My vet said to keep all of my horses on it. And my mini and 26 year old had colic issues prior to using Opti-zyme. You should call your vet and ask. As for not liking it, all mine eat it right with there grain but I do make sure to mix it in well. My vet also has me add some water to my seniors grain. Just enough to moisten it for him. I love the product. I also have my guys on pro-bios. I give them the soft chews, one a day. That is also great for digestion issues.
Gotta love our senior babies! Hope you figure it out.
My 27 year old has trouble emptying gut. He is in a probiotic daily and 1 cup of mineral oil twice daily with senior feed. Think this would belp?
A shopper on Feb 26, 2018
BEST ANSWER: Opti-zyme was recommended to me by our local feed store’s equine nutritionist for my ulcer prone gelding and somewhat anxious mare. It’s one of a few supplements I use to help keep their digestive tracts settled down and it’s not very expensive. I’m sure it wouldn’t hurt to try it but it would probably be best to discuss your horse’s diet with your vet or local horse nutritionist.
I board my horse an hour from me. If I only feed it to him 3 days a week will it do any good?
Carla D on Oct 15, 2015
BEST ANSWER: Hi, anything is better than nothing. Fortunatly my horse is 50 ft. from my house & I feed this almost every morning. If I don't feed this I give her three to four apples. She had a conpaction a year ago so I have been giving her the mix since. She will deficate 3 to 4 times a night.. I have a mix I use with bran, a cup of rolled oats, opti
zyme, antigest, calf-manna & some apple sauce. My horse loves this mixture and will ask for it after I give her her hay. The main thing you want to achieve is to keep those guts moving. A horse, like us if thier guts aren't moving, they are not feeling well. A horse's intestinal track is very sensitive. Good luck and Happy Trails!!
does this come in 10 lb carton????
A shopper on Jan 31, 2018
BEST ANSWER: I'm sorry this is only available in the 3lb.